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(S)-3-Aminobutanenitrile hydrochloride CAS:1073666-54-2 High Optical Purity 99.5% min

(S)-3-Aminobutanenitrile hydrochloride CAS:1073666-54-2 High Optical Purity 99.5% min

(S)-3-Aminobutanenitrile hydrochloride, with CAS number 1073666-54-2, is a high-purity chiral building block widely recognized as the key intermediate for the synthesis of the DPP-4 inhibitor Alogliptin (Benzoate). As a professional supplier, we utilize advanced asymmetric synthesis technology to guarantee exceptional optical purity (e.e. ≥ 99.5%) and stability. We adhere to strict moisture control measures during packaging and storage to ensure the product reaches our global customers in optimal condition.

  • Product Name :

    (S)-3-Aminobutanenitrile hydrochloride
  • CAS No. :

    1073666-54-2
  • Application :

    Orforglipron intermediates
  • Description

Our (S)-3-aminobutanenitrile hydrochloride is a white to off-white crystalline powder and a high-purity chiral amine intermediate. It is a key starting material for the synthesis of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. We employ advanced asymmetric synthesis and crystallization resolution technologies to ensure that the product has extremely high optical purity (e.e. ≥ 99.5%) and chemical stability, meeting the procurement needs of global pharmaceutical companies for high-standard chiral raw materials.

 

 

Properties

- Appearance: White solid

- Special properties: Extremely hygroscopic; readily absorbs moisture and clumps when exposed to air

- Molecular Weight: 120.58 g/mol

- Solubility: Easily soluble in water and methanol, slightly soluble in ethanol, and insoluble in diethyl ether.

- Storage temp:2-8°C

 

 

Specification

Items Specifications
Appearance White solid
Purity 99.5%min
Loss On Drying ≤ 0.5%
Enantiomeric Excess, e.e. ≥ 99.5%
Residue on Ignition ≤ 0.1%
Water Content ≤ 0.2%

 

Applications

(S)-3-aminobutyronitrile hydrochloride (CAS: 1073666-54-2) is a core building block for constructing chiral drug molecules, and plays an irreplaceable role, especially in the synthesis of diabetes drugs.

  • Alogliptin Key Intermediate:

 

This is the highest-value application of the product. It is used in the synthesis of alogliptin benzoate, a potent DPP-4 inhibitor used to treat type 2 diabetes. This intermediate provides the key (S)-configuration chiral center of the drug molecule.

 

  • Application of chiral blocks:

It can be used as a general chiral amine source for the synthesis of other bioactive molecules or drug analogs containing (S)-3-aminobutyl structures.

 

Package

  • #

Standard Packing:  25kg/cardboard drum (lined with polyethylene bag, desiccant recommended)

 

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