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2-Naphthaldehyde CAS:66-99-9

2-Naphthaldehyde CAS:66-99-9

2-Naphthaldehyde, with CAS number 66-99-9, is a high-purity aromatic aldehyde widely recognized as a versatile building block in pharmaceutical and fragrance industries. It serves as the key starting material for the anti-inflammatory drug Nabumetone and is also valued for its orange-blossom-like aroma. As a professional supplier, we ensure consistent quality with low acid content to support global manufacturing requirements.

  • Product Name :

    2-Naphthaldehyde CAS 66-99-9
  • CAS No. :

    66-99-9
  • Application :

    Icotrokinra JNJ-2113 intermediates
  • Description

Our 2-naphthaldehyde is Off-white solid, a high-purity fused-ring aromatic aldehyde. As a multifunctional organic synthesis building block, it combines the chemical reactivity of aromatic aldehydes with the unique structure of a naphthalene ring. We employ optimized oxidation and distillation processes to ensure high purity, low acid value, and excellent color stability, making it widely used in the production of pharmaceutical intermediates, fragrances, and fine chemicals.

 

Properties

- Appearance: Off-white solid

- Melting point:60.3 ~ 60.8 C

- Boiling Point: 160 °C / 19 mmHg

- Density: 1.123 g/cm³

- Solubility: Soluble in ethanol, ether, and chloroform; insoluble in water.

- Storage temp:2-8°C

 

 

 

Specification

Items Specifications
Appearance Off-white solid
Purity 99.9%min
The single biggest unknown impurity ≤ 0.0234%
Acid Value ≤ 1.0%
Water Content ≤ 0.0450%
Residue on Ignition ≤ 0.1%

 

Applications

2-Naphthaldehyde (CAS: 66-99-9) plays an important role in both the pharmaceutical and fragrance industries.

  • Pharmaceutical Intermediates:

Nonsteroidal anti-inflammatory drugs (NSAIDs): It is a key starting material for the synthesis of nabumetone, a widely used anti-inflammatory and analgesic used to treat arthritis.

 

Other drug development: Used in the synthesis of naphthalene derivatives with antifungal or antitumor activity.

  • Flavors & Fragrances:

It has a soft orange blossom and bitter almond-like aroma and is often used as a fixative or in blending floral fragrances such as orange blossom, jasmine, and tuberose. It is also used in soaps and detergents.

 

  • Organic Synthesis and Materials:

Used as a precursor for the synthesis of Schiff base ligands and optoelectronic functional materials (such as electroluminescent materials).

 

Package


  • #

Standard Packing:  25kg/cardboard drum (lined with polyethylene bag)

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